I used it the moment I opened it on my throat since I was experiencing some seasonal allergies - felt noticeably better the next day. I also put it on my feet before bed, a wound that I had on my hand as well as a friends foot where we removed a sliver that had been pestering him for days. No more pain and healing by the end of the day. I'm still discovering all of the benefits! I'm taking a couple of oregano and peppermint oil capsules daily as well for IBS symptoms. You really should research how amazing oregano and peppermint oil are together! Natural ways of healing for the win.